The 6th Air Refueling Wing is organized into five groups: Operations, Maintenance, Mission Support, Medical, and the Wing Staff. Team MacDill includes 28 associate units from all branches of service to include U.S. Central Command, U.S. Special Operations Command, and the 927th Air Refueling Wing.

The presence of these two unified commands and other Mission Teammates creates a unique multi-service community at MacDill, with all branches of service represented. So, although MacDill is an Air Force Base, it is also home to many soldiers, sailors, Marines and coast guardsman.